- On average 1 in every 1000 boys in the United States is born with Jacob's Syndrome.
- Every Day 5-10 boys in the United States are born with Jacob's Syndrome.
- That translates to between 1825 and 3650 new cases yearly.
- Only males can have Jacob's Syndrome and since it is a chromosomal abnormality no one specific group is at a higher risk than another